About the role:
The goal of the CRUK National Biomarker Centre (NBC), is to develop, validate, and implement biomarkers that facilitate the optimisation of cancer patient treatment. In this regard, the NBC is an acknowledged world leader in the study of minimally invasive biomarkers, or liquid biopsies, for improving cancer management. Our biomarker research integrates clinical, experimental and computational science into a highly convergent programme. Translational research and clinical implementation is critical to this biomarker agenda.
An exciting opportunity has arisen for a Scientific Officer to join the Nucleic Acids Biomarker (NAB) team of the NBC. You will work alongside a multidisciplinary team of biologists, clinicians, engineers, and computational scientists. The NAB team is developing new molecular assays from liquid biopsy samples.
Working closely with experienced staff, the appointee will be aligned to the processing, banking and analysis of important clinical trial samples to monitor and evaluate clinical studies and will be required to work under Good Clinical Practice (GCP) regulations. Biomarkers analysed may include circulating cell-free DNA and other liquid biomarkers. All the required training and supervision will be provided.
About you: The successful candidates will possess a degree in molecular biology or relevant scientific discipline (or equivalent relevant experience) plus relevant experience of working in a laboratory environment. Highly desirable is a keen interest in cancer biology, a desire to learn new skills and take forward cancer research. In addition, experience of handling clinical samples, ideally working in a cancer research setting are also desirable. Effective communication, good organizational skills and basic computer skills are essential. Previous experience working in a Good Laboratory Practice (GCP) environment would also be advantageous.
Why choose Cancer Research UK National Biomarker Centre?
We are a leading and highly specialised translational research centre within The University of Manchester (www.manchester.ac.uk), aligned with the Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), and core-funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. In spring 2023 the Institute moved into the state-of-the-art Paterson Building, a £150 million flagship purpose-built biomedical research centre directly attached to The Christie NHS Foundation Trust in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.
Our Centre discovers, develops, validates and qualifies biomarkers in clinical studies and trials that detect cancer earlier and predict and monitor therapy responses to support optimised treatment of patients with cancer. Our advanced research programmes, agnostic to cancer type, develop biomarkers in tissue and less invasive clinical samples such as blood (liquid biopsy) with sophisticated bioinformatic and artificial intelligence solutions for multi-modal laboratory and clinical biomarker data analysis and interpretation. As a bridge between discovery science and clinical research, we are highly collaborative across Manchester, nationally and internationally.
For job description, further particulars and to apply visit JobMarker
For any informal enquiries about this post, please contact Florent Mouliere: florent.mouliere@cruk.manchester.ac.uk
Please note this vacancy will close for applications at 11:59pm on the closing date specified.
